Solid Preparation

Your Professional Solid Preparation Supplier

Reyoung Pharmaceutical Co., Ltd. is a modern, comprehensive pharmaceutical enterprise specializing in the development, manufacturing, and marketing of various pharmaceutical products, including Powder for Injection (including Lyophilized Powder for Injection), Small Volume Injection, Traditional Chinese Medicine (TCM), Tablets, Capsules, Granules, Suppositories, Mixtures, and Active Pharmaceutical Ingredients (APIs).

Professional Team

Reyoung Pharma boasts an exceptional team dedicated to sales and regulatory documentation, with over two decades of expertise in international transactions and product registrations across multiple countries.

Production Capacity

Reyoung operates three factory sites spanning one million square meters, equipped with more than 30 workshops covering nine categories and producing over 400 formulations.

Technological Innovation and Certification

Reyoung Pharma has been awarded the Second Prize for National Technical Improvement, undertaken three National Innovation Projects and three National Torch Plan Projects, and holds 110 patents as well as 60 new drug registration certificates.

Sales Market

Reyoung's products are exported globally, reaching markets in Asia, the Middle East, South America, Europe, Africa, and CIS countries, including Germany, Denmark, Hong Kong, Colombia, Chile, Vietnam, India, among others.

 

 

 
  • Ciprofloxacin Hydrochloride Film-Coated Tablets
    Ciprofloxacin Hydrochloride Film-Coated Tablets 500mg COMPOSITION Each tablet contains Ciprofloxacin Hydrochloride equivalent to Ciprofloxacin 500mg. PHARMACOLOGICAL CLASSIFICATION A...
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  • Amoxicillin Capsules
    Specification: 500mg
    Therapeutic indications:
    Amoxicillin is a penicillin antibiotic, which has good antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus and...
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  • Ampicillin Capsules
    Specification: 500mg
    Therapeutic indications:
    Ampicillin Capsules can be used for respiratory tract infection, urinary system infection, digestive tract infection, otorhinolaryngology...
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  • Cloxacillin Sodium Capsules
    Specification: 500mg
    Therapeutic indications:
    Cloxacillim Sodium Capsules is mainly used to treat mild and moderate infections caused by penicillin-producing and methicillin-sensitive...
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  • Ampicillin and Cloxacillin Sodium Capsules
    Specification: 500mg
    Therapeutic indications:
    Ampicillin and Cloxacillin Sodium Capsules mainly used to treat various infectious diseases caused by bacteria, such as respiratory tract...
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  • Oxacillin Sodium Capsules
    Specification: 500mg
    Therapeutic indications:
    Oxacillin Sodium Capsules can be used to treat penicillin-producing staphylococcal infections, including septicemia, endocarditis, pneumonia...
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  • Amoxicillin Tablets
    Specification: 500mg
    Therapeutic indications:
    Ampicillin Tablets is suitable for the following infections caused by sensitive bacteria (strains that do not produce β -lactamase).
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  • Amoxicillin Film-coated Tablets
    Specification: 500mg
    Therapeutic indications:
    Ampicillin Film-coated Tablets is indicated in the treatment of infections caused by susceptible non penicillinase producing strains.
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  • Amoxicillin Dispersible Tablets
    Specification: 500mg
    Therapeutic indications:
    Ampicillin Dispersible Tablets can be used for respiratory tract infection, urinary tract infection, gastrointestinal tract infection, skin...
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  • Amoxicillin and Clavulanate Potassium Tablets
    Specification: 625mg
    Therapeutic indications:
    Ampicillin and Clavulanate Potassium Tablets is used for short-term treatment of infection suspected to be caused by amoxicillin-resistant...
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  • Penicillin V Potassium Tablets
    Specification: 250mg
    Therapeutic indications:
    Penicillin V Potassium Tablets is suitable for mild and moderate infections caused by penicillin-sensitive strains, including tonsillitis,...
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  • Oxacillin Tablets
    COMPOSITION
    - Tablet : Oxacillin (INN) sodium salt,equivalent to oxacillin 500 mg.Excipients :Dextrin, sodium starch glycolate, magnesium stearate.
    - Powder for oral suspension :...
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Specications

Active Pharmaceutical Ingredient

CAS NO.

Molecular Formula

Defination

Oxacillin Sodium Capsules

7240-38-2

C19H20N3NaO6S

(2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate (1:1:1)

Cloxacillin Sodium Capsules

642-78-4

C19H17ClN3NaO5S

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, (2S,5R,6R)-, hydrate (1:1:1)

Amoxicillin Capsules

34642-77-8

C16H18N3NaO5S

[2S-[2a,5a,6b[S*]]]-6-[[Amino[4-hydroxyphenyl]acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt

 

Types of Solid Preparation

The solid preparations produced by our company mainly include the following types:

 
 

Tablets

Tablets are the most prevalent form of oral solid dosage products, and their diverse range includes immediate-release, sustained-release, and controlled-release varieties, each designed to meet specific drug delivery needs and enhance patient outcomes.

 
 
 

Chewable Tablets

Chewable tablets have gained popularity in recent years due to their convenience and ease of use for individuals who have difficulty swallowing compressed tablets. These tablets are designed to be chewed and swallowed, allowing for the active ingredient to be released and absorbed through the lining of the mouth.

 
 
 

Capsules

Capsules are a versatile oral drug delivery system that offers a range of options for drug formulation and delivery. They consist of a shell made of either gelatin or polymer material that encloses the API and dry powder ingredients. Capsules come in two main types: hard and soft. Hard capsules are made of gelatin, while soft capsules can be made from a variety of materials, including vegetable oil and other polymers.

 

 

 
 
Benefits of Solid Preparation
Cloxacillin Sodium Capsules

Convenience and Patient Compliance

Opting for solid preparation forms offers a multitude of benefits for pharmaceutical companies looking to balance efficiency and cost-effectiveness. Solid preparation forms, such as tablets and capsules, allow for improved patient compliance as they offer convenient administration, allowing patients to take their medication without the need for healthcare professional involvement. This convenience leads to more effective treatment outcomes and improved patient satisfaction.

Ampicillin Capsules

Accurate Dosing and Uniform Drug Content

Solid preparation forms allow for precise dosing, and ensure the accurate delivery of the prescribed amount of medication. They provide uniform drug content, minimizing variations in dosage and enhancing consistency in drug administration.

 

 

Amoxicillin Capsules

Stability and Shelf Life

Another advantage of solid preparation forms is their extended shelf life and stability. Compared to liquid or semisolid formulations, solid preparation forms are generally more stable and have a longer shelf life. They can retain potency over time and are less susceptible to degradation or contamination when stored correctly. This stability ensures that the medication remains effective throughout its intended shelf life, making solid preparation a reliable solution for pharmaceutical companies looking to meet the demands of global supply chains while maintaining product quality and ensuring patient safety.

Ciprofloxacin Hydrochloride Film-Coated Tablets

Clinical Development and Control Processes

Choosing solid preparation forms also offers competitive advantages to pharmaceutical companies in terms of clinical development, production cost, and control processes. solid preparation forms allow for easier clinical development as they are simple to manufacture and can be easily scaled up. Moreover, solid preparation forms can be produced at a lower cost than other drug formulation types, as they require less equipment and fewer processing steps.

 

 

 

Solid Preparation Production Process

 
Direct blending process

The first step in the manufacturing process usually involves screening the drug substance and excipients to eliminate the large agglomerates. These raw materials are then mixed in blenders to form a uniform blend. A powder lubricant is added to minimize mechanical friction and improve the efficiency of downstream processes. This blend – if free flowing – can then be filled into pouches, capsule shells, or compressed into tablets.

Wet granulation

Sometimes direct blends are not free flowing due to particle size, shape, or cohesive properties of the drug substance. In such cases, the drug is first wet granulated where the drug and a portion of excipients are mixed along with a solvent (often water) using a high shear or a low shear process to form wet granules. These granules are then dried using tray ovens or fluidized bed dryers. The dried granules are then sized using appropriate screens to form free-flowing dry granules. These are then mixed in blenders with the remaining excipients to form a uniform blend. This blend can then be filled in pouches, capsule shells, or compressed into tablets.

Dry granulation

In some cases, wet granulation is not feasible due to the unstable nature of the drug substance. Instead, the drug substance can be dry granulated using a roller compaction machine. The drug is mixed with certain excipients and passed through rolls to form a brittle ribbon. This ribbon is then broken and sized using milling equipment. The resulting granules can then be further processed to form the finished dosage form.

Pelletization

A variety of processes are available to formulate the drug substance into near spherical, free-flowing pellets. One method is by coating the API on inert beads composed of sugar/starch or microcrystalline cellulose. The pellets can be encapsulated into hard gelatin capsules.

Coating

Tablets, pellets, or capsules can be further coated with functional polymers to modify the drug release.

Molding

Products such as troches and lozenges can be prepared by melting the API with suitable excipients and pouring the mixture into molds. The molded drug is then cooled to form the final product.

 

 
 
Our Working Process
01.

Select A Project

Please choose the product you need based on the existing products.

02.

Project Analysis

We will analyze your needs based on the product you have chosen and provide you with a suitable proposal.

03.

Deliver Sample

After you confirm the product, we will deliver the sample to you as soon as possible.

04.

Order Confirmation

We have a formal and detailed order format.

 

Packaging and Shipping

Packaging

Plastic medicine bottle, paper box packaging

Shipping

● For small quantity, shipment is prefered to shipping with express by DHL, UPS, FedEx or Special line by USPS, DGHY, Chinapost etc

● For regular mass production, shipment by sea, air, door to door etc.

 

 

Our Factory

 

Reyoung is one of the top 50 companies of the national medical industry in recent years. The International Business Department is founded in 1997. Reyoung dedicates 25 years in exporting products to about 90 countries and NGOs covering Africa, Asia, South America, ect.

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Certificate

 

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FAQ

 

Q: What to watch out for when taking penicillin?

A: Depending on the type of penicillin, common side effects may include mild nausea or diarrhea, headache, or vaginal itching. Signs or symptoms of an infection for which you are being treated — or unrelated symptoms — also may be mistaken as an allergic drug reaction.

Q: What are the main stages involved in penicillin production?

A: Penicillin biosynthesis is described into three main steps; catalytic step, oxidative, and exchange of different chains. The catalytic step involves an ACV synthetase enzyme that condenses the lateral chain of cysteine, valine, and alpha aminoadipate into tripeptide ACV.

Q: What not to do when taking penicillin?

A: These products can interact with antibiotics and affect how your body absorbs them. Be careful with grapefruit and citrus juices, and wait at least three hours after taking your prescription before consuming dairy products.

Q: How long does penicillin take to work?

A: You'll usually take phenoxymethylpenicillin 4 times a day to treat an infection. In most cases you'll start to feel better in a few days.

Q: Are liquid or solid vitamins better?

A: While more research is required, liquid preparations such as liposomal, alcohol and water-based herbal tinctures, and other oil and water-based liquid vitamins seem to provide exceptional efficacy compared to more traditional pills, tablets, and capsules.

Q: Is it better to take vitamins in the morning or at night?

A: The best time to take vitamins is often debated, but generally, it's recommended to take them in the morning with a meal, especially for multivitamins and those that contain B vitamins. However, fat-soluble vitamins like A, D, E, and K are best taken with a meal containing fat for better absorption, and some people may prefer taking them before bed if they experience stomach upset with daytime consumption.

We're professional solid preparation manufacturers and suppliers in China, featured by quality products and good price. Please feel free to wholesale solid preparation made in China here from our factory. Contact us for more details.

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