Penicillin Solid Preparations
Reyoung Pharmaceutical Co., Ltd., established in 1966, is a modern comprehensive pharmaceutical company. Reyoung is given the title of National Trustworthy Company for Contract and Credit, Grade AAA Credit Company and Credit Company of Shandong Medical Industry. In the past 50 years, Reyoung inherits the mission "Reyoung Pharma., Benefit the public", insists the business concept "Innovation is the basis, Product quality is first". Never stop exploration and innovation, forging ahead with determination, and realizing the sustainable healthy development.
Why Choose Us
Our Certifications
All the workshops have been passed the cGMP. Reyoung also pass ISO system certificates. Reyoung also passed the overseas audit like PIC/S GMP.
Our Factory
Reyoung consists of 3 factory sites (covering an area of 1 million m2), possessing more than more than 30 workshops (9 categories, and 400 strengths) .
Credit Enterprise
Reyoung Pharmaceutical Co., Ltd., established in 1966, is a modern comprehensive pharmaceutical company. Reyoung is given the title of National Trustworthy Company for Contract and Credit, Grade AAA Credit Company and Credit Company of Shandong Medical Industry.
Business Philosophy
Reyoung inherits the mission "Reyoung Pharma., Benefit the public", insists the business concept "Innovation is the basis, Product quality is first". Never stop exploration and innovation, forging ahead with determination, and realizing the sustainable healthy development.
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Amoxicillin CapsulesSpecification: 500mgread more
Therapeutic indications:
Amoxicillin is a penicillin antibiotic, which has good antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus and... -
Ampicillin CapsulesSpecification: 500mgread more
Therapeutic indications:
Ampicillin Capsules can be used for respiratory tract infection, urinary system infection, digestive tract infection, otorhinolaryngology... -
Cloxacillin Sodium CapsulesSpecification: 500mgread more
Therapeutic indications:
Cloxacillim Sodium Capsules is mainly used to treat mild and moderate infections caused by penicillin-producing and methicillin-sensitive... -
Ampicillin and Cloxacillin Sodium CapsulesSpecification: 500mgread more
Therapeutic indications:
Ampicillin and Cloxacillin Sodium Capsules mainly used to treat various infectious diseases caused by bacteria, such as respiratory tract... -
Oxacillin Sodium CapsulesSpecification: 500mgread more
Therapeutic indications:
Oxacillin Sodium Capsules can be used to treat penicillin-producing staphylococcal infections, including septicemia, endocarditis, pneumonia... -
Amoxicillin TabletsSpecification: 500mgread more
Therapeutic indications:
Ampicillin Tablets is suitable for the following infections caused by sensitive bacteria (strains that do not produce β -lactamase). -
Amoxicillin Film-coated TabletsSpecification: 500mgread more
Therapeutic indications:
Ampicillin Film-coated Tablets is indicated in the treatment of infections caused by susceptible non penicillinase producing strains. -
Amoxicillin Dispersible TabletsSpecification: 500mgread more
Therapeutic indications:
Ampicillin Dispersible Tablets can be used for respiratory tract infection, urinary tract infection, gastrointestinal tract infection, skin... -
Amoxicillin and Clavulanate Potassium TabletsSpecification: 625mgread more
Therapeutic indications:
Ampicillin and Clavulanate Potassium Tablets is used for short-term treatment of infection suspected to be caused by amoxicillin-resistant... -
Penicillin V Potassium TabletsSpecification: 250mgread more
Therapeutic indications:
Penicillin V Potassium Tablets is suitable for mild and moderate infections caused by penicillin-sensitive strains, including tonsillitis,... -
Oxacillin TabletsCOMPOSITIONread more
- Tablet : Oxacillin (INN) sodium salt,equivalent to oxacillin 500 mg.Excipients :Dextrin, sodium starch glycolate, magnesium stearate.
- Powder for oral suspension :... -
Amoxicillin for Oral SuspensionAmoxicillin Suspension is an antibiotic. Theactive ingredient is called amoxicillintrihydrate. This belongs to a group ofmedicines called penicillin.read more
Amoxicillin Suspension is used to...
Susceptibility Test Interpretive Criteria
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Susceptibility Test Result Interpretive Criteria |
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Pathogen |
Disk Diffusion |
Minimal Inhibitory |
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S |
I |
R |
S |
I |
R |
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Staphylococcus spp. |
≥29 |
- |
≤28 |
≤0.12 |
- |
≥0.25 |
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Streptococcus spp. (beta-hemolytic group) |
≥24 |
- |
- |
≤0.12 |
- |
- |
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Streptococcus pneumoniae (non-meningitis isolates) |
≤0.06 |
0.12-1 |
≥2 |
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Quality Control
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Acceptable Quality Control Ranges |
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Microorganism |
Disk Diffusion |
Minimal Inhibitory |
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Staphylococcus aureus ATCC® 25923 |
26-37 |
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Staphylococcus aureus ATCC® 29213 |
0.25-2 |
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Streptococcus pneumoniae ATCC® 49619 |
24-30 |
0.25-1 |
Specification
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Penicillin Solid Preparations |
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Advantages of Penicillin Solid Preparations
Good Bactericidal Activity: Penicillin is a narrow-spectrum bactericidal antibiotic that can inhibit the formation of the cell wall of Gram-positive bacteria during the bacterial reproduction period, so that the bacterial cell wall is broken and the intracellular osmotic pressure decreases, resulting in the death of the bacterial body, so it has a good bactericidal effect;
Rapid Onset Of Action: Penicillin belongs to concentration-dependent antibiotics, its bactericidal efficacy depends on the level of blood concentration, the drug can quickly reach the effective blood concentration within a short period of time after entering the human body, and the onset of action is relatively fast, which is conducive to the play of antibacterial effect;
Strong Targeting: Penicillin has good antibacterial activity against gram-positive bacteria and sensitive gram-negative bacteria, low toxicity to animal cells without cell walls, and strong effect on reproducing bacteria;
Types of Penicillin Solid Preparations
Natural penicillins
Natural penicillins are found in the world around us (they aren’t made by people). Scientists isolate (purify) just the penicillin from where it’s found to make it into medications.
Semi-synthetic penicillin
Scientists alter penicillin’s natural form to make more effective antibiotics. These are called semi-synthetic penicillins. They include penicillinase-resistant penicillins, aminopenicillins and extended-spectrum penicillins.
Combination medications
Penicillins are often combined with other medications into one drug to help them work better.

Production Process of Penicillin Solid Preparations
Strain fermentation
• Inoculate Penicillium flavum producing fungi on solid medium and incubate at 25°C for 7-10 days to obtain Penicillium spore culture.
• Inoculate the spores into the sterilised medium in the seed vessel by making a suspension of the spores with sterile water, passing through sterile air, stirring and incubating at 27°C for 24-28 hours.
• Inoculate the seed culture into the sterilised medium containing phenylacetic acid precursor in the fermentation tank, pass through sterile air, stir and incubate at 27°C for 7 days. During fermentation it is necessary to replenish the phenylacetic acid precursor and the appropriate amount of medium.
Extraction and purification
• The penicillin fermentation broth was cooled and filtered. The filtrate was subjected to multi-stage countercurrent extraction with butyl acetate in an extractor at pH 2-2.5 to obtain the butyl ester extract.
• The butyl ester extract was transferred to a buffer solution of pH 7.0-7.2 and then to butyl ester, decoloured with activated carbon, added with a salt-forming agent and distilled azeotropically to give penicillin G potassium salt.
• Penicillin G sodium salt is prepared by passing penicillin G potassium salt through an ion exchange resin (sodium type).
Solid preparation
• Penicillin G potassium or sodium salt obtained by extraction is dried to give penicillin solid powder.
• The penicillin solid powder can be further processed into solid dosage forms such as tablets and capsules as required. This usually involves process steps such as tablet pressing, filling and coating.
Certificate









Packaging
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Storage |
Store at temperatures below 30°C in a dry place, protected from light. |
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Packaging |
50 Vials in a box. |
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Validity |
Three years |
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Manufactured by |
Reyoung Pharmaceutical Co.,Ltd. |
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MOQ |
100000 Vials |
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Qualification Certificate |
COPP,GMP |
Our Customization Process
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Deliver Sample
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Order Confirmation
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FAQ
We're professional penicillin solid preparations manufacturers and suppliers in China, featured by quality products and good price. Please feel free to wholesale penicillin solid preparations made in China here from our factory. Contact us for more details.
7240-38-2, 69-52-3, Amoxicillin Film coated Tablets






