Suppository

Your Professional Suppository Supplier

 

Reyoung Pharmaceutical Co., Ltd., established in 1966, is a modern comprehensive pharmaceutical company. Reyoung is given the title of National Trustworthy Company for Contract and Credit, Grade AAA Credit Company and Credit Company of Shandong Medical Industry. In the past 50 years, Reyoung inherits the mission "Reyoung Pharma., Benefit the public", insists the business concept "Innovation is the basis, Product quality is first". Never stop exploration and innovation, forging ahead with determination, and realizing the sustainable healthy development.

 

Why Choose Us

Our Certifications

All the workshops have been passed the cGMP. Reyoung also pass ISO system certificates. Reyoung also passed the overseas audit like PIC/S GMP.

Our Factory

Reyoung consists of 3 factory sites (covering an area of 1 million m2), possessing more than more than 30 workshops (9 categories, and 400 strengths) .

Credit Enterprise

Reyoung Pharmaceutical Co., Ltd., established in 1966, is a modern comprehensive pharmaceutical company. Reyoung is given the title of National Trustworthy Company for Contract and Credit, Grade AAA Credit Company and Credit Company of Shandong Medical Industry.

Business Philosophy

Reyoung inherits the mission "Reyoung Pharma., Benefit the public", insists the business concept "Innovation is the basis, Product quality is first". Never stop exploration and innovation, forging ahead with determination, and realizing the sustainable healthy development.

 

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    Acetaminophen Suppository, available in 125mg and 250mg formulations, possess analgesic and antipyretic properties. Its mechanism involves inhibiting central cyclooxygenase, particularly COx-2,...
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  • Diclofenac Suppository
    Diclofenac Suppository, a non-steroidal anti-inflammatory drug, offers effective relief from severe pain and inflammation. Ideal for conditions like acute gout, musculoskeletal disorders, and...
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Parameters Evaluation

 

 

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Advantages of Suppository
 
 
 

Bypass first-pass metabolism

 

Drugs administered via suppositories can avoid first-pass metabolism in the liver, which may improve bioavailability for certain drugs.

 
 

Alternative route for patients with difficulty swallowing

Suppositories are useful for patients who have difficulty swallowing oral medications, such as young children, the elderly, or those with swallowing disorders.

 
 

Suitable for unconscious or nauseous patients

Suppositories can be administered to patients who are unconscious or experiencing nausea and vomiting, making them a practical alternative to oral medications.

 
 

Local treatment

 

Suppositories can deliver drugs directly to the site of action for local treatment, such as treating haemorrhoids or vaginal infections.

 

 

Diclofenac Suppository
Suppository Bases

• Bases must have a solid form at room temperature


• It should possess a less irritating property


• They should be able to produce an inflamed sensation in body cavities like the vagina, urethra, etc


• It should be stable during storage conditions. Changes in colour, shape and odour must be adhered to


• They should be soft so that they can be handled easily


• It must be nonreactive with drugs and additives so that harmful reactions can be avoided


• It should have good emulsification properties


• The acidic acid value must lie between less than 0.2 and zero


• It should have an iodine value of less than 7


• Water-dispersible bases are the hydrophilic bases having a mixture of non-ionic

 

Types of Suppository

 
Rectal Suppository

Suppositories inserted in the rectum are referred to as rectal suppositories. The suppository melts in the body through rectal insertion and directly enters the bloodstream. This rectal suppositories method is very useful for people in their old age or for very young ones who may not be able to take oral medications. Also, for hemorrhoid treatment, rectal suppositories are used.

Vaginal Suppository

Suppositories directly inserted in the vagina are referred to as vaginal suppositories. They are usually inserted with the help of a plastic applicator. These vaginal suppositories turn liquid and start inducing their effect as they go into the vagina due to the temperature change. These suppositories have proved effective in treating fungal infections and vaginal dryness. Its size and the chemical formula it is made of sometimes governs the time it would take to dissolve and starts working in the vagina. There are also contraceptive suppositories taken to avoid unwanted pregnancy. To make this work, females should insert the contraceptive suppository 10 minutes before sex.

Urethral Suppository

Suppositaries which are inserted in the urethra are known as urethra suppositories. These are generally used for treating erectile dysfunction or sexual problems in males. It helps the blood to flow into the penis so as to get an erection. Its dose depends on person to person according to their medical condition and response to the suppositories. These suppositories show their effect within 5 to 10 minutes when inserted and result in an erection lasting about 30 to 60 minutes. One should not use more than two daily doses, i.e., in 24 hours.

Nasal Suppository

Suppositories which are inserted in the nose are known as nasal suppositories. These are generally 1 gram in weight.

Ear Suppository

Suppositories which are inserted in the ear are known as ear suppositories. These are also known as aurinaries. These are also 1 gram in weight and cylindrical in shape.

Characteristics of Suppositories
 

Easy to melt at room temperatures

Can be easily inserted into body cavities, including the rectum, vagina, urethra, nose, and ear

They are known to melt drugs for their administration

They have a systematic effect

 

 

Certificate

 

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Packaging

 

 

Storage

Store at temperatures below 30°C in a dry place, protected from light.

Packaging

50 Vials in a box.

Validity

Three years

Manufactured by

Reyoung Pharmaceutical Co.,Ltd.

MOQ

100000 Vials

Qualification Certificate

COPP,GMP

 

Our Customization Process
1

Select A Project

Please choose the product you need based on the existing products

2

Project Analysis

We will analyze your needs based on the product you have chosen and provide you with a suitable proposal

3

Deliver Sample

After you confirm the product, we will deliver the sample to you as soon as possible

4

Order Confirmation

We have a formal and detailed order format

 

 

FAQ

 

Q: What not to do after taking suppository?

A: Avoid exercise or vigorous movement for 60 minutes after inserting the medication. Do not use petroleum jelly, such as Vaseline, to lubricate the suppository. This stops it from melting. Only use water, or a water-based lubricant.

Q: What are the precautions in the administration of suppositories?

A: Wash your hands before and after use. Take off the foil wrapping. Wet the tip of the suppository with cold water to make it easier to use. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach.

Q: How long does suppository work?

A: Bisacodyl suppositories in 15 minutes to 1 hour. carbon dioxide–releasing suppositories in 5 to 30 minutes. glycerin suppositories in 15 minutes to 1 hour. senna suppositories in 30 minutes, but may not occur for some individuals for up to 2 hours.

Q: How often can you safely use suppositories?

A: A person will usually need to insert only one suppository before they begin to see the effects. They should not insert more than one suppository per day.

Q: How long should I sit on the toilet after a suppository?

A: Close your legs and sit or lie, holding the suppository for about 15-30 minutes to allow time for it to melt. If you have an urge to empty as soon as you have inserted the suppository, try to 'hang on' a little longer as you will have better results.

Q: What are the rules for suppositories?

A: Spread your butt cheeks open with one hand to locate your rectum. Press the suppository up into your butthole (with the narrow end going in first). The suppository should be at least one-half inch in for children or 1 inch in for adults. Try to stay still for at least a few minutes so it can melt/dissolve.

Q: What is the best time of day to use a suppository?

A: Initially it is best to try to use one suppository at a time convenient to you. First thing in the morning is often most successful as this is a time when the urge to empty your bowel may be strongest. Alternatively use one in the evening. Sometimes people require two suppositories.

Q: Why lay on the left side for suppository?

A: Doctors recommend lying on your left side. This takes advantage of the natural angle of the rectum and makes it easier to insert the suppository. Always wash your hands and use gloves. Lubricate the finger of the glove with K-Y jelly or a similar product.

Q: How long does it take for a vaginal suppository to absorb?

A: Step Six: Sit or lie still for about 10 to 15 minutes to allow the medicine to dissolve.

Q: How to make a suppository work faster?

A: Try to avoid passing stool for up to 60 minutes after inserting the suppository, unless it is a laxative. Not passing stool gives the medication enough time to enter the bloodstream and start working.

Q: How long should a patient remain lying down after inserting a suppository?

A: Remain lying down for about 15 minutes to avoid having the suppository come out. Talk to your care team about the use of this medication in children.

Q: Why is the end of a suppository often concave?

A: Suppositories are manufactured in a torpedo shape with a pointed end (apex) and a blunt end. The blunt end is often concave forming a useful indention for the tip of a finger to push against. due to nausea and or vomiting. Suppositories also provide a useful route for medication in children who have needle phobia.

Q: Can you push a suppository in too far?

A: Gently but firmly, push the suppository past the sphincter. The sphincter is the muscular opening of the rectum. For adults, push it in about 3 inches or far enough in so that it will not pop out. For children, depending on their size, push it in about 2 inches.

Q: What happens if you don't poop after a suppository?

A: If you do not have a bowel movement within 12 hours after using this medication, or you experience rectal bleeding, contact your care team. These may be signs of a more serious condition.

Q: How do I make sure my suppository stays in?

A: Insert the suppository, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about 1/2 to 1 inch in infants and 1 inch in adults. (If not inserted past this sphincter, the suppository may pop out.)

We're professional suppository manufacturers and suppliers in China, featured by quality products and good price. Please feel free to wholesale suppository made in China here from our factory. Contact us for more details.

Acetaminophen Suppository, Paracetamol Suppository, Diclofenac Suppository