Diclofenac Sodium Enteric-coated Tablets

Specification: 25mg; 50mg; 100mg
Therapeutic indications:
1. This product is used to relieve rheumatoid arthritis, osteoarthritis, spinal joint disease, gouty arthritis, rheumatoid arthritis and other arthritis of the joint swelling pain symptoms.
2. For the treatment of non-articular soft tissue rheumatic pain, such as shoulder pain, tenosynovitis, bursitis, myalgia and post-exercise injury pain.
3. For acute light and moderate pain, such as after surgery, trauma, strain, dysmenorrhea, toothache, headache, etc.
4. It has antipyretic effect on fever of adults and children.

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APIS

Active Pharmaceutical Ingredient	Latin Name	Molecular Formula	Defination	Structural Formula
Diclofenac Sodium Enteric-coated Tablets	Sodium Diclofenac Enteric-coctais Tabulae	C14H11Cl2NO2	Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, sodium salt (1:1)

Product Specifications

Products	Specification	Vomume of vials	Packing form
Diclofenac Sodium Enteric-coated Tablets	Inner-house lastest version	Yellow, round, enteric-coating tablets.	10caps/blister, 10blisters/box

API mixing

Filling

Vial sterilization

Dosage

Take it orally.

1. As a routine dose, the initial daily dose is 100-150mg. For mild cases or patients requiring long-term treatment, the daily dose is 75-100mg. The daily dose is usually divided into 2-3 doses.

2. For primary dysmenorrhea, the usual daily dose is 50-150mg, divided into times. The initial dose should be 50-150mg, and if necessary, the dose can be increased over several menstrual cycles to a maximum of 200mg/ day. Treatment should begin as soon as symptoms appear and continue for several days, depending on the symptoms.

Matters need attention

Gastrointestinal reaction: is the most common adverse reaction, about 10% of the people taking the drug, mainly for stomach discomfort, burning sensation, acid return, poor appetite, nausea, etc., stop the drug or symptomatic treatment can disappear. A few of them may develop ulcers, bleeding, perforation.

Nervous system manifestations include headache, dizziness, lethargy, excitement, etc.

Cause edema, oliguria, electrolyte disorders and other adverse reactions, light can disappear after withdrawal and corresponding treatment.

Other rare cases have transient elevation of serum transaminase, and very few have jaundice, rash, arrhythmia, granulocytopenia, thrombocytopenia, etc., which can be recovered after withdrawal.

Matters need attention

1. Patients with known allergy to this product.

2. Patients with a history of gastrointestinal bleeding or perforation after the use of NSaids.

3. It is prohibited for the treatment of perioperative pain during coronary artery bypass grafting (CABG).

4. Patients who have asthma, urticaria or allergic reactions after taking aspirin or other non-steroidal anti-inflammatory drugs.

5. Patients with active gastrointestinal ulcer/bleeding, or who have had recurrent ulcer/bleeding in the past.

6. Patients with severe heart failure.4. Other rare cases have transient elevation of serum transaminase, and very few have jaundice, rash, arrhythmia, granulocytopenia, thrombocytopenia, etc., which can be recovered after withdrawal.

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