APIS
| Active Pharmaceutical Ingredient | CAS NO. | Molecular Formula | Definition | Structural Formula |
| Oxacillin Sodium | 7240-38-2 | C19H20N3NaO6S | sodium,(2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrate | ![]() |
Products Specications
| Products | Specification | Vomume of vials | Packing form |
| Oxacillin Sodium for Injection 0.5g,1g | USP | 7ml mould vials | 50vials/box |
| 10vials/box | |||
| 1vial/box | |||
| 10ml mould vials | 50vials/box | ||
| 20vials/box | |||
| 1vial/box |
Oxacillin Sodium for Injection is a semi-synthetic penicillin with resistance to penicillinase (β-lactamase). Here are the key details:
Composition:
Active ingredient: Oxacillin Sodium.
Chemical formula: C19H18N3NaO5S·H2O.
Molecular weight: 441.44 g/mol.
Indications:
Used for treating infections caused by penicillinase-producing Staphylococcus aureus:
Septicemia (bloodstream infections)
Endocarditis (heart valve infections)
Pneumonia
Skin and soft tissue infections



Dosage and Administration:
Intramuscular injection:
Adults: 4–6 g daily, divided into 4 doses.
Children: Weight-based dosing (12.5–25 mg every 6 hours).
Intravenous infusion:
Adults: 4–8 g daily, divided into 2–4 doses.
Severe infections: Daily dose may increase to 12 g.
Adverse Effects:
Allergic reactions (such as urticaria), serum sickness-like reactions.
Nausea, vomiting, elevated serum aminotransferases (with intravenous use).
Central nervous system toxicity (seizures) at high doses.
Precautions:
Perform a thorough allergy history and penicillin skin test before use.
Cross-allergies may occur with other penicillins or cephalosporins.
Use cautiously in patients with asthma, eczema, or urticaria.
Monitor renal function in severe renal impairment.



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