Here is a more detailed introduction of Nimodipine for Injection for different parts.
Composition:
Nimodipine for Injection is generally contained of Ethanol, polyethylene glycol 400, sodium citrate, anhydrous citric acid, and water for injection.
Indications:
◇ Main indication:
It is widely used for the prevention and treatment of ischemicneurological deficits caused by cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
◇ other indications:
It also can be used in other cerebrovascular diseases such as cerebral as well as in the treatment of sudden sensorineural hearing loss.
Administration:
◇Dosage: Orally.
● For patients with a body weight of ≥70 kg, the initial dose is 1 mg/h (approximately 15 μg/kg/h). After 2 hours, if well - tolerated, the dose can be increased to 2 mg/h (approximately 30 μg/kg/h).
● For patients with a body weight of <70 kg or those with unstable blood pressure, the initial dose is 0.5 mg/h (approximately 7.5 μg/kg/h). If well - tolerated, it can be increased to 1 mg/h.
Adverse Reactions:
Common Adverse Reactions:
◇ Hypotension: A decrease in blood pressure is a relatively common side effect.
◇ Headache: Some patients may experience headaches during treatment.
◇ Nausea: Gastrointestinal discomfort, mainly presenting as nausea, can occur.
◇ Liver Function Abnormalities: There may be changes in liver function indicators.
Serious Adverse Reactions:
◇ Severe Hypotension and Shock: In rare cases, significant drops in blood pressure leading to shock may occur.
◇ Bradycardia: A slow heart rate can be a serious adverse event.
◇ Cerebral Edema: Although uncommon, it can have serious consequences.
Storage and Production
◇Storage:
It should be stored at a temperature below 25°C, protected from light. Once opened, it should be used immediately.
◇Production:
It is produced by pharmaceutical companies such as Qingdao Jinfeng Pharmaceutical Co., Ltd. The common specifications include 50 ml: 10 mg.
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