AFGF
AFGF is a multifunctional and potent cytokine that plays an important role in promoting the metabolism of fibroblasts and the formation of collagen.
AFGF can promote the growth and proliferation of skin tissue. By binding to specific receptors on the cell surface, it regulates the division, proliferation, and growth differentiation of skin epithelial, endothelial, and stromal cells, promotes cell metabolism, and enhances oxidative stress; It can promote the rapid growth and reproduction of cells related to skin damage, and regulate the synthesis, secretion, and decomposition of intercellular matrix; Can promote the regeneration of stratum corneum cells, accelerate the repair of skin stratum corneum and stromal layer, and promote the growth of human skin cells; It can enhance the synthesis of proteins and cellular metabolism in skin cells, delay skin cell aging, promote the repair and growth of epidermal cells, and make the skin smooth and plump.
Since the discovery of fibroblast growth factors (FGFs) in 1940, after more than half a century of continuous understanding and exploration, its mechanism of action has now been preliminarily understood FGFs are a protein family consisting of 23 members (FG-FI-FGF2301). Acid fibroblast growth factor (aFCF), also known as FGFI, is present in kidney and brain tissues in young children. The physiological functions and biological effects of aFGF are diverse, especially in promoting the growth and development of the body, repairing tissue damage, and other aspects. Studies have shown that aFGF has a promoting effect on tumor cell proliferation, with rich expression on the cell surface of tumor tissue, and is closely related to the occurrence and development of tumors. So, we can filter from. AFGF antagonizes skin and hands, providing a new approach for tumor treatment. [1]
AFGF freeze-dried powder is widely used in the beauty field, leading the new trend of healthy skincare in China's high-end beauty market. In recent years, significant achievements have been made in the application of freeze-dried powder growth factors in China. Represented by Jinan University and Jiyuan Biotechnology, brands such as Jinan University Meisu and Zuokang have led the trend of AFGF freeze-dried powder growth factor skincare in China.
BFGF
Biological functions of BFGF:
The biological effects of BFGF are divided into two main parts: in vivo and in vitro. The in vitro effects are very strong, and fibroblasts, bone cells, chondrocytes, vascular endothelial cells, adrenal cortex and medullary cells, neurons, and glial cells have strong activity in promoting cell division and proliferation [10]. It can exert its effects at low concentrations (1 mg · ml-1) in vitro cell culture. BFGF is an important mitogenic factor and an inducer of morphogenesis and differentiation. Its main biological functions include: (1) acting as a vascular growth factor; (2) Promote wound healing and tissue repair; (3) Promote tissue regeneration; (4) Participate in nerve regeneration, etc.
EGF
The application of EGF in beauty:
EGF has a significant effect on shrinking pores and anti wrinkle. The reason is that EGF can promote the growth and division of various cells in epidermal tissue, making epidermal cells full and restoring their youthful state. It can also promote the growth ability of collagen and repair aging and broken collagen elastic fibers, so it is praised by many scientists as a "beauty factor". However, the initial production of EGF was extremely low, with a selling price of nearly $2 million per gram, greatly limiting its application in the beauty field. In 1992, James Laboratories in the United States added EGF to cosmetics, pioneering a new field of biological beauty using EGF for wrinkle removal and anti-aging, marking the arrival of the era of biological gene beauty.