Advantages Of Freeze-dried Powder Injection

Compared with general powder injections, freeze-dried powder injections have better stability: because freeze-dried powder injections are made and stored in a vacuum state, with almost no oxygen in the vacuum state, drugs will not be oxidized; The freeze-dried powder needle has extremely low water content (<0.01%) and will not be hydrolyzed; The production process of freeze-dried powder needles is strictly sterile (reaching the level 100 standard) and will not be contaminated, so the stability of freeze-dried powder needles is good. Freeze dried powder injections also take effect faster than regular powder injections and have higher bioavailability. This is because the special production process of freeze-dried powder injection allows the drug to be evenly dispersed in an ice shelf formed by freeze-drying with chitosan and other substances. This structure expands the surface area of the drug, allowing it to come into contact with more bacteria per unit time, thus having quick acting functions. The special ice shelf structure formed by chitosan can enable drugs to exist in nanocapsules, which are released upon reaching the lesion site through blood circulation, thereby improving the bioavailability of drugs.
The high-tech of freeze-dried powder needles is reflected in: in addition to vacuum, aseptic, extremely low water content, and high technological content in the production process of quick freezing and sublimation, freeze-dried powder needles also have the following high-tech content:
(1) Drug microencapsulation or formation of liposomes: By screening freeze-dried carriers, adjusting the shape of ice shelves and pore sizes, drugs can be microencapsulated or formed into liposomes. By screening different microcapsules and liposomes, drugs can achieve rapid, targeted, or controlled release effects.
(2) By adjusting the carrier and freeze-drying process, two drugs can be combined into a complex salt under specific environmental conditions. The latter can enable both drugs to reach the lesion simultaneously, exerting a synergistic effect, greatly improving the bactericidal efficacy of antibacterial drugs. And the compound salt enhances the stability of the drug.